Select Page

Pharmaceuticals

For further information and pricing, please get in touch with us.

Identification of molecular signals using static SIMS on powders

SIMS can be used to confirm the presence of a drug or to make brand identification where different formulations exist

Overview

SIMS can be used to confirm the presence of a drug or to make brand identification where different formulations exist; a branded product may contain additional substances or a counterfeit product could show contamination.

The presence of binding, dehydrating or filling agents can also provide a unique fingerprint. In the example below, Al and Na come from the pill forming material. The high sensitivity of the analyser allows very low beam currents to be employed, keeping below the static SIMS limit preserves the high mass fragments required for unequivocal identification.

Powder Analysis

Powders may be analysed using SIMS, both for bulk composition and core-shell structure. Powders can be mounted using either conductive adhesive tape, dispersion, pill formation or pressing into indium sheet.

Further Reading

Icon

MXene improves the stability and electrochemical performance of electropolymerized PEDOT films 6.69 MB 0 downloads

MXene improves the stability and electrochemical performance of electropolymerized...
Icon

Growth of conductive Si-doped α-Ga2O3 by suboxide molecular-beam epitaxy 5.68 MB 0 downloads

Growth of conductive Si-doped α-Ga2O3 by suboxide molecular-beam epitaxy ...
Icon

Impact of oxygen and hydrogen traces on the focused ion beam sputter rate and secondary ion mass spectrometry intensity detection of graphite 2.66 MB 3 downloads

Impact of oxygen and hydrogen traces on the focused ion beam sputter rate and secondary...
Icon

On the knowledge of depth effect on secondary ion mass spectrometry profiling of deuterium-implanted fusion matrices 4.51 MB 12 downloads

On the knowledge of depth effect on secondary ion mass spectrometry profiling of...
Icon

On the knowledge of depth effect on secondary ion mass spectrometry profiling of deuterium-implanted fusion matrices 4.51 MB 14 downloads

On the knowledge of depth effect on secondary ion mass spectrometry profiling of...
Icon

Probing dynamic degradation and mass transport in solid-state sodium-ion batteries using operando simultaneous dual-polarity SIMS 3.42 MB 14 downloads

Probing dynamic degradation and mass transport in solid-state sodium-ion batteries...
Icon

Application of Secondary Ion Mass Spectrometry for Analysis of Decorative Coatings on Fancy Goods Accessories 1.33 MB 106 downloads

Application of Secondary Ion Mass Spectrometry for Analysis of Decorative Coatings...
Icon

Alkali-metal-based molecular-ion secondary ion mass spectrometry for precise quantitative analysis of low-dimensional materials without standards 3.01 MB 98 downloads

Alkali-metal-based molecular-ion secondary ion mass spectrometry for precise quantitative...
Icon

The crucial role of defect structure in understanding the electrical properties of spark plasma sintered antimony doped barium stannate 1.74 MB 124 downloads

The crucial role of defect structure in understanding the electrical properties of...
Icon

Silicon-doped β-Ga2O3 films grown at 1 μm/h by suboxide molecular-beam epitaxy 1.33 MB 137 downloads

Silicon-doped β-Ga2O3 films grown at 1 μm/h by suboxide molecular-beam epitaxy ...